Article Archive







Volume 1, Issue 3



A Review of Underlying Causes of Maternal Deaths in Benue North Central Nigeria

Journal of Infertility and reproductive Biology, 2013, Volume 1, Issue 3, Pages 42-47, Full Text in PDF (75.9 KB)


Alobo GI, Ochejele S, Ngwan SD


Department of Obstetrics and Gynecology, Federal Medical Centre Makurdi, Nigeria.



Most maternal death reviews are on impact assessment rather than the underlying factors. Maternal death review that goes beyond the number has not been widely studied in Nigeria despite the high contribution of underlying factors to maternal deaths in the country. To determine the underlying causes of maternal death in the facility. This was a comprehensive facility based maternal death review at Federal Medical Centre Makurdi from 1st January to 31st December 2012. Factors surrounding each maternal death were analyzed prospectively to learn a lesson from each death by exploring gaps at the levels of the hospital, patient and the community. The MMR was 1381/100000 live births. Hospital factors were implicated in 39.3% and they were predominantly lack of ICU 19.0%, poor management of the referral chain 19.0% inability to assess complications fully 15.5%, laboratories challenges 11.9% and lack of obstetric skills (inexperience) 8.3%. Patient’s factor occurred in 32.1% and they were non booking (34.6%), non use of family planning (26.9%) and decision delays (32.7%). The Community factors occurred in 28.6% and they included transportation problem (28.6%), socio-cultural factors (28.6%), gender inequality (16.7%), inhibitory abortion laws 11.9% and illiteracy 9.5%. Maternal mortality was high in the facility because of the complex interaction of underlying factors with obstetric complications.


Keywords: Maternal mortality review, underlying factors, Benue state



The Histomorphometric Effects of Maternal Diabetes on Rat Offspring’s Ovaries at the Puberty


Journal of Infertility and reproductive Biology, 2013, Volume 1, Issue 3, Pages 48-53, Full Text in PDF (248 KB)


Zabiholla Khaksar1,  Gholamali Jelodar1, Hooman Hematian2,  Mohamad Poorahmadi3


1- Department of Basic sciences, School of Veterinary Medicine, ShirazUniversity, Shiraz, Iran

2- Department of Veterinary sciences, Yasooj Branch, Islamic Azad University, Yasooj, Iran

3- Department of Basic Sciences, Jahrom medical university, Jahrom, Iran



In pregnant mothers, maternal diabetes occurs when the pancreas cannot produce enough insulin, which leads to increased blood glucose concentration in the mother and consequently in the foetus, causing various neonatal problems. This study was conducted to evaluate the effects of maternal diabetes on foetal ovarian structure. Sixteen adult female rats were allocated into two equal groups. Diabetes was induced in one group by alloxan agent. Both groups became pregnant by natural mating. 60 days after birth, the female offspring were terminated, the body weight and blood glucose of the animals measured and their ovaries removed. Various histological parameters were determined using histological techniques. Results revealed a significant increase in body weight and blood glucose in the offspring of the diabetic mothers (ODM) compared to that of controls. The weight, volume and diameter of the ovary and ovarian capsule thickness were decreased in the ODM group. The number and diameter of primary, preantral, antral and preovulatory follicles and corpora lutea were decreased in ovaries in the ODM. Maternal hyperglycaemia exhibited deleterious effects on the reproductive system of their offspring.


Keywords: Gestational Diabetes, Rat, neonates, Ovary, Follicle




Knowledge and Practice of Prostate Health of Men in the Work Place


Journal of Infertility and reproductive Biology, 2013, Volume 1, Issue 3, Pages 54-57, Full Text in PDF (70 KB)


Adesanya O.A1, Shittu L.A.J2, Awobajo F.O3, Otulana O.J1, Adesanya R.A


1. Department of Anatomy, Faculty of Basic Medical Sciences, Olabisi Onabanjo University, Ikenne Campus,

Ogun State, Nigeria.

2. Department of Anatomy, Benue State University, Markudi, Nigeria.

3. Department of Physiology, College of medicine, University of Lagos, Idi Araba, Lagos.

4. St Ives Hospital, Allen Avenue Ikeja, Lagos, Nigeria.



This study was carried out to determine knowledge, attitude and perception of the prostate health among male employees of a College of medicine in a university setting. Findings from a postal questionnaire showed a high level of ignorance about the prostate gland in the body. 45% of the respondents (TR) do not know what the prostate gland is, and 54.4% do not know where it was situated in the body. On the Diet rating: 36.4%  of the respondent  enjoyed  fatty food,63.6%  liked red meat, and 72.7%  liked fried food, 36.4%  indulged in alcohol and smoking which  are not good  for the prostate health. On the prostate symptoms score: 11.4%  had a severe symptom score, while 56.85% had a moderate  symptom score while 31.8%  of the respondent had a moderate symptoms. Conclusion: despite widespread prevalence of prostate problems among aging men, many men especially in south-western, Nigeria, had little knowledge of what is called prostate and associated problems among aging men and possible preventive measures available to help. The good side of this finding is that men in this part of the world consume diets which are rich in fiber, which is a good development for the prostate health though many of them has a flare for fatty and fried food.



Keywords: Prostate Health, Knowledge, Diet, Workplace, International prostate symptoms score (IPSS)




Efficacy of Rescue ICSI after Total Fertilization Failure in Conventional IVF


Journal of Infertility and reproductive Biology, 2013, Volume 1, Issue 3, Pages 58-62, Full Text in PDF (75.5 KB)


Maryam Eftekhar, Soheila Pourmasumi, Mohammad-Hossein Razi


Research and Clinical Center for infertility, Shahid Sadughi University of Medical Sciences, Yazd, Iran.



Partial or complete fertilization failure after IVF was reported in 5-10% of cycles. Total fertilization failure in patients with normal sperm parameters is rare but very stressful incident after IVF. To  rescue the IVF cycles after total fertilization failure, ICSI of unfertilized oocytes after initial insemination has been reported.We reviewed a 2 years experience of rescue ICSI and analyzed the cycles outcomes. Cycles with total fertilization failure using mature oocytes with normal morphology, which had no evidence of fertilization 24 hours after IVF were selected for this study and reinsemination by ICSI was performed. 15 rescue ICSI cycles were included in our study. After rescue ICSI fertilization rate per cycle was 54.32%. Also  5.53±4.15 embryos were obtained  and 2.54±o.34 embryos were transferred in each cycles.  But no  pregnancy was reported after fresh embryo transfer. This study showed that day1 rescue ICSI is not a good option for prevention of complete fertilization failure after IVF procedure.

Key words: Rescue ICSI, conventional IVF, oocyte, fertilization failure.


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