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J. Infertil. Reprod.
Biol. Volume 3, Issue 3, 2015 |
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Investigation of plasma cytokine levels and
endometrial tissue leukocytes in recurrent pregnancy loss Journal of Infertility and reproductive Biology, 2015, Volume 3, Issue 3, Pages 192-198, | Full Text in PDF (99 KB)
Mehmet Simsek1,
Zehra Sema Ozkan1*,
Derya Deveci2, Fulya
Ilhan3, Nusret Akpolat4 1. Firat University School of Medicine, Department of
Obstetrics and Gynecology, Elazig, Turkey 2. Firat University School of Health Services, Elazig, Turkey 3. Firat University School of Medicine, Department of
Immunology, Elazig, Turkey 4. Inonu
University School of Medicine, Department of Pathology, Malatya, Turkey Abstract Women usually
desire to have wider birth intervals, hence adopt family planning methods
such as oral pills, Intrauterine device, Injections, barrier methods,
sterilization etc. which are most commonly practiced in the country. Among
these tubectomy is one of the safest permanent
operative procedure; complications are rare and occur in less than 1% of all
female sterilization operations. Tubectomy gives
almost absolute protection against unwanted childbirths as compared with
temporary methods. The objective of this study was to find out the choice for
the acceptance of tubectomy as permanent method of
contraception. This study was carried
out in the Gynaec OPD of NIUM Hospital during the
year of 2014-2015. Total 600 women were enrolled in the study and detailed
history was obtained regarding the issues and type of family planning method
adopted. The collected data was recorded and analyzed. Out of 600 women 344
(57.33%) women adopted temporary methods, whereas 256(42.66%) adopted
permanent sterilization (tubectomy). Among
temporary methods 137(22.83%) were on OCP, 70 (11.66%) were on IUCD, 62
(10.33%) were on barrier methods and 52 (8.66%) were not used any methods,
whereas 256 (42.66%) had tubectomy. Most of the
women i.e. 108 (42.18%) had tubectomy operation
after two children and least women i.e. 50 (19.53%) had tubectomy
operation after five children. It was observed in Bangalore city
that the most of women accepted tubectomy operation
especially after two or three children. It may be due to sensitivity of women
towards financial status, better education or carrier of their children or
better health. Keywords: Recurrent pregnancy loss, Natural
killer, Macrophage, Endometrial leukocytes, Cytokines Comparison of
ovarian response between PCOS and Non-PCOS patients undergoing ICSI with
antagonist protocol Journal of Infertility and reproductive Biology, 2015, Volume 3, Issue 3, Pages 199-207, | Full Text in PDF (127 KB) Krishnapillai Jayakrishnan1*,
Divya Nambiar1, Jesin
Leo Fency1 1. KJK
Hospital, Trivandrum, Kerala, India Abstract Antagonists
have been shown to be better than agonists in general and in the PCOS
infertility with lower rate of OHSS.
This study is a retrospective observational study and patient record
review of PCOS and Non-PCOS groups of patients who entered ART over a duration of 3 years. On comparison of
ovarian response in both groups, the mean number of oocytes
obtained was more in the PCOS group but the number of mature oocytes obtained was significantly less. A higher
fertilization rate and cleavage rate was observed in the non- PCOS patients
i.e. 82.3% and 73.2% respectively versus 71% and 58.7% in the PCOS group
which was statistically significant. There were no patients with OHSS in the non-
PCOS group, whereas in the PCOS group we had 10 patients with mild OHSS, 4
(6%) patients with moderate OHSS and only 1 (1%) patient with severe OHSS. In conclusion the pregnancy rate was
comparable in patients with PCOS undergoing GnRH
antagonist ovarian stimulation compared with non-PCOS patients in whom the
same controlled ovarian stimulation was used. Of importance is the fact that
there was only one case of severe ovarian hyperstimulation
syndrome in the PCOS group, making the use of the GnRH
antagonist an attractive option in this high-risk group of patients. Keywords: GnRH antagonist, PCOS, Ovarian response, Cleavage rate,
OHSS |
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Assisted conception, endometrial tuberculosis with
secondary infertility, treatment and subsequent live birth. A case report Journal of Infertility and reproductive Biology, 2015, Volume 3, Issue 3, Pages 208-212, | Full Text in PDF (108 KB) Aamir Javed1*,
Ashwini L.S1, Debashree
Ganguly2, Farnaz Mozafari3,
Murugan.S4, Sneh Sagar5 1. Base Fertility Medical
Science Pvt Ltd. MIG 1/14, KHB
Colony, Bangalore, India 2. Jahar
Infertility Research Institute, VIP Park, Deshbandhunagar,
Baguiati, Kolkata, India 3. R&D in Life Sciences
Biotechnology Research Lab, DSI, KS Layout Bangalore, India 4. Institute of
Biomedical Research, # 23/6, Shivaji Street, 1st
Floor, T. Nagar, Chennai, India 5. Genelon
Institute of Life Sciences Pvt. Ltd., No-1160, Yelanka
Old Town Bangalore, India Abstract Female genital tuberculosis is a latent cause of
infertility in our milieu and is barely looked for as part of usual
evaluation of infertility. With a radical incidence of Tuberculosis in the
face of the developing countries, it is important to always have genital
tuberculosis in mind particularly when no erstwhile reason is found for the
infertility. Woman genital tuberculosis is a significant cause of
secondary infertility in developing countries or where tuberculosis is
endemic. In the current study we present a case in which endometrial
tuberculosis was a cause of secondary infertility of almost 10 long years.
From February 2013 to October 2013, we performed, laparoscopy, trans- vaginal
Study, pelvic scan for infertile patient. The patient had secondary infertility;
therefore, she underwent the process of the endometrial biopsy and
hysteroscopy. The laparoscopic discovery confirmed normal ovaries and uterus
in the patient; evenough the fallopian tube of the
patient was normal. Hysteroscopy results concluded that the endometrial layer
was atrophied in the patient, and biopsy results revealed the presence of
acid-fast bacilli using Zeihl-Neelsen stain further
confirmation by the ABI™ Rt-PCR. We
concluded that patients with endometrial tuberculosis possibly have no clear
filed record of tuberculosis or may have proof evidence of tuberculosis
grazes somewhere else in the body. Histopathological confirmation from the biopsies of
pre-menstrual endometrial tissue or expression of tubercle bacilli in
cultures of endometrial curetting or menstrual blood is required to reach a
decisive diagnosis of the disease or indications. When our patients were
treated with antituberculosis treatment (ethambutol
800 mg + isoniazid 300 mg + pyrazinamide
750 mg + rifampicin 450 mg.) for 6
months they regained with the endometrial tuberculosis, and achieve pregnancy
via assisted conception. Gynaecologists in
developing countries must consider genital tuberculosis as an important cause
of secondary infertility. Keywords: Mycobacterium Tuberculosis,
Anti-TB therapy, Assisted reproduction Impact of Smoking on Sperm’s DNA and Assisted
Reproductive Techniques Outcome Journal of Infertility and reproductive Biology, 2015, Volume 3, Issue 3, Pages 213-219, | Full Text in PDF (84 KB) Mohamed Faris1, Taimour
Khalifa2, Sayed Bakry3* 1. Faris Medical Center for
Infertility and Human Reproduction, Heliopolis, Cairo, Egypt 2. Department of Dermatology and Venereology,
School of Medicine, Al Azhar University, Nasr City,
Cairo, Egypt 3. Laboratory of Molecular Biology and Embryology, Zoology
Department, School of Science, Nasr City, Cairo, Egypt Abstract The effect of smoking on Assisted
Reproductive Technology (ART) results in male was considered as a deleterious
factor in pregnancy outcome among IVF
patients. Male smoking is associated
with lower success rate in ICSI and IVF couples. Smoking significantly
decreased live birth rates and has a deleterious effect on sperm’s DNA. This
study was designed to evaluate the effect of male cigarettes smoking on the
outcome of ICSI and IMSI, referring to clinical pregnancy, implantation and miscarriage
rate. Therefore a total of 255 couples were
diagnosed with severe oligo-astheno-teratozoospermia,
3 years of primary infertility, the woman aged 30 years or younger and an undetected
female factor were randomized to IVF micro insemination treatments. Males
were classified according to smoking into two major groups: group 1 (109)
smokers and group 2 (146) non-smokers. The smoker group including (44 male)
admitted for ICSI procedures and (65 male) admitted for IMSI procedure.
While, non-smoker group included (76 male) and (70 male) were admitted for
ICSI and IMSI respectively. A comparison between the two groups was based in
terms of pregnancy, miscarriage and implantation rates. Student t-test was
adopted to assess the significant differences between the two groups. The results of our study
showed no significant difference in clinical pregnancy, implantation and
miscarriage rate between smoker and non-smokers men. While, the difference was high significance in clinical pregnancy
and implantation in IMSI group when compared to ICSI group and lowest
significance difference was recorded in miscarriage rate in IMSI group when
compared to ICSI group. In conclusion this study shaded more light on the
effect of cigarettes smoking on male fertility and the cutting edge
procedures used to solve the issue of frequent ICSI failure in the infertile
couples. It also showed that clinical pregnancy and implantation rates are
increased and miscarriage rate decreased in non- smoker couples male when
IMSI procedure was used for them. Keywords: Male infertility, Sperm DNA, Cigarettes smoking,
IMSI, ICSI Effect of Age at Marriage on Inter Pregnancy Spacing- An
Observational Study Journal of Infertility and reproductive Biology, 2015, Volume 3, Issue 3, Pages 220-225, | Full Text in PDF (99 KB) Tabassum.Kotagasti1,2*, Nishat
Rias1 1. Reader, Department of Amraze Niswan wa Qabalat
(OBG), National Institute of Unani Medicine, Bangalore,
India 2. PG Scholar, Dept of OBG, NIUM, B’lore Abstract Birth
Spacing or interval between births is significantly influenced by social and
biological factors like age, education, race, age at marriage, parity, child
mortality, gender composition etc.
This paper illustrates the influences of age at marriage on inter pregnancy space. The objective of this Observational study
was to find out the birth-spacing pattern in respect of age at marriage. The
study was carried out in the Dept. of Obstetrics and Gynaecology,
National Institute of Unani Medicine and Hospital
during the year of 2014 to observe the influence of age of mother on spacing
of children. This study consisted of 130 women of parity three. A detailed history was taken regarding the
age, age at marriage, parity and spacing and data was recorded. It was
observed that Early married had longer birth interval between
marriages and first birth, 1st to 2nd and 2nd
to 3rd i.e. 1.96, 2.09 and 2.76 respectively, whereas women with
average age at marriage had shorter interval i.e.1.83, 1.75 and 1.87 years
respectively. In present study a
complex relationship between age at marriage and inter pregnancy interval was
found as both early and average age at marriage to some extent affects the
spacing of children. Keywords: Age at marriage, Early and average, Influence,
Parity, Spacing Journal of
Infertility and Reproductive Biology Copyright 2013,
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