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J. Infertil. Reprod.
Biol. Volume 3, Issue 4, 2015 |
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Association study of Yq11 AZFc
subdeletion and recurrent pregnancy loss-A study in
South Indian males Journal of Infertility and reproductive Biology, 2015, Volume 3, Issue 4, Pages 226-233, | Full Text in PDF (113 KB)
Kavitha Papanna, Shivaprasad H Satyanarayan,
Vineeth V Satidevi, Suttur. S Malini Molecular
Reproductive and Human Genetics Laboratory, Department of Studies in Zoology,
Manasagangotri, Mysore, Karnataka, India Abstract The
etiologies in recurrent pregnancy loss were focused only towards females with
less consideration of male factors. This study was undertaken to analyze the
association of AZF deletions in
idiopathic recurrent pregnancy loss among South Indian couples. Eighty males
whose female partners with the history of two or more idiopathic recurrent
pregnancy loss were considered as a case group and fifty male volunteers with
proven fertility as a control group. Semen and blood samples were collected from
the entire study subject and examined for functionality of the sperm along
with routine semen analysis. Standard PCR was performed for Yq microdeletion
analysis in AZFa, b and c regions along with AZFc subdeletion analysis. RPL
group showed statistically significant lower scores for total motility and
sperm function test than the control. Abnormal semen
parameters were reported in 18.8% among RPL males. AZFc subdeletions were reported in 8.75% of
RPL males, none of the RPL individuals including control group showed no
deletion for AZFa, AZFb and AZFc. We observed subnormal sperm function scores
in AZFc sub deleted subjects. No significant association was observed between
routine semen parameters and AZFc subdeletions. Our results revealed the potential association
of abnormal sperm functioning and AZFc subdeletion in the idiopathic RPL
cases in South Indian population. Keywords: Recurrent pregnancy loss, Sperm
function test, Y chromosome, AZF microdeletions, AZFc subdeletions Ectopic pregnancy in tubal stump after ipsilaterial
salpigo-oohorectomy: an unusual and rare case report Journal of Infertility and reproductive Biology, 2015, Volume 3, Issue 4, Pages 234-236, | Full Text in PDF (190 KB) Ranjan Agrawal* , Parbodh Kumar Department of Pathology, Rohilkhand
Medical College & Hospital, Bareilly (UP); India Abstract A 35-years-old female presented with severe
abdominal pain, vomiting and spotting per vaginum since one day following 2
months amenorrhoea. Ultrasound abdomen revealed right sided tubal pregnancy.
She gave a history of right sided salpingo-oophorectomy 15 years back. The
case is unusual due to the ectopic occurring on the same side of
salpingectomy and also since the ectopic occurred after such a long interval. Keywords:
Ipsilateral, Ectopic pregnancy,
Tubal stump, Salpingo-oophorectomy |
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Methyl farnesoate induced ovarian vitellogenin
syntehsis in freshwater rice field crab Oziothelphusa senex senex Fabricious Journal of Infertility and reproductive Biology, 2015,
Volume 3, Issue 4, Pages 237-244, | Full
Text in PDF (176 KB) B. Srinivasa Reddy, P. Ramachandra Reddy Department of Biochemistry, Yogi Vemana University,
Vemanapuram, Kadapa – 516 003, A.P. INDIA Abstract Reproduction in crustaceans is under the control of
an array of hormones, internal and external factors including the terpenoid
hormone methyl farneosate (MF). In the present study an attempt was made to
induce vitellogenesis in crab Oziotelphusa
senex senex by injecting MF on every alternative day up to 28 days at a
concentration of 10-8 moles/crab. The concurrent control group
received vehicle on par with MF injected group and eyestalk ablated group as
positive control were maintained. The crabs were sacrificed on 7th,
14th, 21st and 28th day of experiment to
check the stage of reproduction and to measure the ovarian vitellogenin
levels. Significant (p<0.001) increase was observed in ovarian
vitellogenin levels in MF injected and eye stalk ablation groups on 7th,
14th, 21st and
28thday of experiment, when compared to concurrent controls which
are in immature stage throughout the experimentation. Also observed increase
in the ovarian maturation and ovarian vitellogenin levels are significant in
MF injected group than the eyestalk ablated group.
Observed two reproductive cycles in the MF injected group of with a mean days
of 11±2 in 28 days experiment. Whereas positive control group (ESX) is about
to complete one reproductive cycle by the end of the experiment. The results
of the present study clear indicate that MF induces vitellogenin synthesis
there by ovarian maturation in crab by direct and/or indirect action. Keywords: Crab, Ovarian maturation, Vitellogenin, Eyestalk
ablation, Methyl farnesoate Early clomiphene citrate for
ovulation induction in polycystic ovary syndrome Journal of Infertility and reproductive Biology, 2015, Volume 3, Issue 4, Pages 245-249, | Full Text in PDF (78 KB) Mohamed Hussain1, Amr H. Yehia1,
Ibrahim A. Abdelazim1,2, Assem A. M.
Elbiaa1, Khaleed M.
Abdelrazak1, Mohamed M. Farghali1 1. Department of Obstetrics and Gynaecology, Ain Shams
University, Cairo, Egypt. 2. Department of Obstetrics and Gynaecology, Ahmadi
Hospital, Kuwait Oil Company (KOC), Kuwait. Abstract This study was
designed to evaluate effect of starting Clomiphene Citrate (CC) in oligomenorrheic women with PCOS
immediately after progestin therapy without waiting withdrawal bleeding
versus CC on day 2 of the withdrawal
bleeding. Eighty Four (84) women with PCOS,
oligo/amenorrhea were studied. Studied women received oral progestin to
induce withdrawal bleeding. Women who started CC immediately after oral
progestin without waiting withdrawal bleeding were included in group I and
women who started CC at the same dose and for the same duration, but on day 2
of the induced withdrawal bleeding were included in group II. Transvaginal
ultrasound scan (TVS) for folliculometry and endometrial thickness was
performed after end of CC treatment and repeated every 48 hours till mature
follicle (s) was detected. Results
showed that rate of detection of
one mature follicle was slightly higher in early CC group compared with late
CC group 25 (59.5%) versus 21 (50%); respectively), but this difference was
not significant. Endometrial thickness at detection of mature follicle was
significantly higher in early CC group compared with late CC group (10.42 ±
1.93 mm versus 8.7 ± 1.77; respectively), clinical pregnancy rate was
slightly higher in early CC group compared with late CC group (6(14.3%)
versus 4(9.5%); respectively); but this difference was not significant. It was concluded that early CC administration for ovulation induction in
PCOS seems to be associated with significantly thicker endometrium, slightly
higher ovulation and pregnancy rates, compared to the conventional CC
administration. Keywords: Clomiphene citrate, Ovulation induction, Polycystic
ovary syndrome Influence
of estrogen, progesterone and their synthetic derivatives on ovarian
functions Journal of Infertility and reproductive Biology, 2015, Volume 3, Issue 4, Pages 250-254, | Full Text in PDF (76 KB) Mohammed Farman1*, Shiv Kumar Tripathi2,
Deepthi K Babu3, Sumanta Nandi 2, V Girish Kumar1 1. Department of Veterinary Biochemistry, Veterinary
College, Bangalore-560024, India 2. National Institute of Animal Nutrition and Physiology,
Bangalore-560030, India 3. Sathyabama University Chennai-600119, India. Abstract Estrogen and progesterone, the main sex steroids mostly bound to
plasma proteins while circulating in the bloodstream. Only unbound estrogen and progesterone are
biologically active. Gonadotrophins like Luteinizing
hormone (LH) and Follicle stimulating hormone (FSH)
promote ovulation and stimulate secretion of the sex hormones-estrogen and progesterone from
the ovaries. These sex steroids stimulate the target organs of the
reproductive system and inhibit as well as around the time of ovulation
stimulate gonadotropin secretion. Since estrogen circulating in the blood can
negatively feed-back to reduce
circulating levels of FSH and LH, most oral contraceptives contain a
synthetic estrogen, along with a progestin. The present
article overviews the role of estrogen,
progesterone and their synthetic derivatives on ovarian functions.
Keywords: Estrogen, Progesterone, Progestin, Ovary Journal of
Infertility and Reproductive Biology Copyright 2013,
All Rights Reserved Dorma Trading,
Est. Publishing Manager Address:
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