Home | About Us | Journal Scope | Editorial Board | Reviewers | Article Archive | Guide for Authors | Contact Us | Online Submission
J. Infertil. Reprod. Biol. Volume 6, Issue 1, 2018
Mitochondrial Fatty Acid Transport System and its Relevance to Ovarian Function Journal of Infertility and Reproductive Biology, 2018, Volume 6, Issue 1, Pages 1-3, https://doi.org/10.47277/JIRB/6(1)/1|Full Text in PDF and HTML (267 KB) Mona Sharma Department of Reproductive Biology, All India Institute of Medical Sciences, New Delhi-110029, India Abstract: Mitochondrial fatty acid oxidation is integral to folliculogenesis and oocyte maturation. Mitochondrial fatty acid transport system includes molecules such as 3-hydroxy-4-trimethylamino butyrate or carnitine, organic cation transporter novel 2 (OCTN2), carnitine palmitoyl transferase (CPT1), CPT2, and carnitine-acylcarnitine translocase (CACT). These are essential molecules that play an important role in the transport of activated long chain fatty acids from cytosol to the mitochondrial matrix where these subsequently undergo beta-oxidation. It has been well established that fatty acid metabolism is vital for follicles and oocyte growth. This review highlights the possible role of mitochondrial fatty transport acid system in ovarian function. Keywords: Oocytes, Carnitine, Mitochondria, Fatty acids
Journal of Infertility and Reproductive Biology Copyright 2013, All Rights Reserved Dorma Trading, Est. Publishing Manager Address: Diera.P.O.Box:8433 Dubai-United Arab Emirates. Telephone +971507580755